Power of Likelihood Ratio Tests for Heterogeneity of Intraclass Correlation and Variance in Balanced Half-Sib Designs

On the use of linear regression and maximum likelihood for QTL mapping in half-sib designs.

Methods of identification of quantitative trait loci (QTL) using a half-sib design are generally based on least-squares or maximum likelihood approaches. These methods differ in the genetical model considered and in the information used. Despite these differences, the power of the two methods in a daughter design in very similar. Using an analogy with a one-way analysis of variance, we propose ...

the washback effect of discretepoint vs. integrative tests on the retention of content in knowledge tests

در این پایان نامه تاثیر دو نوع تست جزیی نگر و کلی نگر بر به یادسپاری محتوا ارزیابی شده که نتایج نشان دهندهکارایی تستهای کلی نگر بیشتر از سایر آزمونها است

Likelihood Ratio Tests in Multivariate Variance Components Models

ii Acknowledgements In preparing this thesis I am indebted to many people. First of all, I wish to express my sincere gratitude to Professor Chihiro Hirotsu, my thesis supervisor, for his guidance and encouragement. Komaki for their valuable comments and suggestions. Finally I am very grateful to my parents for their continual encouragement, and to my wife, Hisae, who has shared both my joy and...

Likelihood Ratio Tests for

Maximum likelihood estimation of linkage disequilibrium in half-sib families.

Maximum likelihood methods for the estimation of linkage disequilibrium between biallelic DNA-markers in half-sib families (half-sib method) are developed for single and multifamily situations. Monte Carlo computer simulations were carried out for a variety of scenarios regarding sire genotypes, linkage disequilibrium, recombination fraction, family size, and number of families. A double hetero...